Endocrine Abstracts

Background: Diabetes is the most prevalent chronic metabolic disorder in children and adolescents, and incidence rates for both type-1 and type-2 diabetes are increasing worldwide. In recent years, the number of patients with type 1 diabetes is increasing mainly due to children under 5-years-old.Objective: To study the epidemiological indicators of T1DM among children of the Republic of Armenia (RA) from 2007 to 2016. Methods: Retrospective analysis of t...

Introduction: Incidence of type 1 diabetes mellitus (T1DM) is rising steadily around the globe, including Armenia. It is one of the most common autoimmune and metabolic disorders in pediatric population, resulting from autoimmune destruction of pancreatic β-cells leading to insulin deficiency. Gut microbiota (GM) is reportedly involved in the pathogenesis of T1DM likely by influencing the immune response with the help of arginine-metabolizing enzymes. Arginase i...